CAS No.205444-22-0 | 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine
Name: 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine CAS No.205444-22-0 MF: C6H2ClF3IN MW: 307.44 Purity:97% Package: 5g,25g,100g,500g,1kg,25kg Worldwide Delivery
Categories：
Analytical Chemicals
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Product introduction
Introduction and application of CAS No.205444-22-0 | 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine
2-Chloro-4,6-difluoro-pyridine is an electrophilic compound that can react with nucleophiles to form covalent bonds. This reaction is known as nucleophilic substitution and it can be used in the synthesis of organic compounds. The diisopropylamide of lithium is a popular reagent for this purpose because it is inexpensive, highly reactive, and easily purified by distillation. In particular, 2-chloro-4,6-difluoro-pyridine reacts quantitatively with lithium diisopropylamide to form 4-(2-chloro-4,6-difluoro)pyrimidin-2(1H)-ones in tetrahydrofuran.
Synonyms:
2-chloro-4-iodo-6-trifluoromethyl-pyridine;
Specification of CAS No.205444-22-0 | 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine
|
ITEMS |
SPECIFICATION |
|
CAS No. |
205444-22-0 |
|
MF |
C6H2ClF3IN |
|
MW |
307.44 |
|
Boiling point |
230.469ºC at 760 mmHg |
|
Flashing point |
93.185ºC |
|
Density |
2.047g/cm3 |
|
acidity coefficient(pKa) |
-4.47±0.10(Predicted) |
|
refractive index |
1.54 |
Package of CAS No.205444-22-0 | 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine
Package:100g; 500g; 1kg; 25kg;bulk package
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.205444-22-0 | 2-Chloro-4-iodo-6-(trifluoromethyl)pyridine
… directed metallation of azines and diazines (pyridines, pyrimidines, pyrazines, pyridazines, quinolines, benzodiazines and carbolines). Part 1: Metallation of pyridines …
F Mongin, G Quéguiner - Tetrahedron, 2001 - Elsevier
… When the mixture of 3- and 4-lithio derivatives resulting from deprotonation with LDA at −110C
was quenched with iodine, only 2-chloro-4-iodo-6-(trifluoromethyl)pyridine was formed. …
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